Is it safe to take nyquil with benadryl

Benadryl (diphenhydramine) is an older, first generation antihistamine, which can cause more side effects like drowsiness, dizziness, and impaired coordination. Newer antihistamines, like Claritin (loratadine), Allegra (fexofenadine), Zyrtec (cetirizine), and Xyzal (levocetirizine), may still cause some drowsiness, but to a less extent than ...

Can i take Nyquil with Benadryl? ChaCha Answer: Benadryl is also an antihistamine so it is not recommended to take both because you a... Best Answer: Looks like you did your home work about those 2 products. Benadryl is an antihistamine that you already have in NyQuil. Take the NyQuil alone.Is It Safe to Take an Antihistamine for Sleep Every Night? Medically reviewed by Suzanne Stevens, MD — By Corey Whelan — Updated on April 24, 2023 EffectivenessCommon diphenhydramine side effects may include: dizziness, drowsiness, loss of coordination; dry mouth, nose, or throat; constipation, upset stomach; dry eyes, blurred vision; or. day-time drowsiness or "hangover" feeling after night-time use. This is not a complete list of side effects and others may occur.Overview. In the vast majority of individuals, it is safe to take Allegra (fexofenadine) the same day as NyQuil, even though Allegra is an antihistamine and NyQuil contains an antihistamine. However, they generally should not be taken at the same time. At the very least, they should be separated from one another by at least four to six hours to ...Long-term side effects. Over-the-counter (OTC) Benadryl is approved for temporary or short-term use and is not intended for long-term use. There is very little scientific research about the long ...Expired Benadryl for six months should still work, provided it has been kept in its original container and a cool, dry place away from light. It might not be as effective as before, but there's very little chance it will cause you any harm. Read on to know whether or not you can take an expired Benadryl, its safety, what happens when you take ...50 mg. 100 mg. The typical hydroxyzine dosage for adults with insomnia is 50 mg daily, taken at least 30 minutes before bedtime. Your healthcare provider will recommend the appropriate dosage based on your condition. Meanwhile, Benadryl has two doses—25 mg and 50 mg. The average dose of Benadryl for sleep issues is 50 mg daily, taken orally.Key points. DayQuil and NyQuil can be taken on the same day, but should not be taken at the same time as they share some of the same drugs (acetaminophen, dextromethorphan) The short answer here is that you can take them Nyquil & Dayquil together, but not at the same time. In this context, the "same time" means any time within 4 to 6 hours of ...

Yes. Sudafed (pseudoephedrine) is a decongestant, while Benadryl (diphenhydramine) is an antihistamine. "Antihistamines and decongestants work differently and are often combined in cold and ...According to WebMD, there are no drug interactions between Tylenol and Benadryl, so they can be taken at the same time. However, a personal doctor or pharmacist should always be in...Maximum dose: 50mg. Motion sickness: 25mg to 50mg up to three or four times a day as needed. Maximum: 300 mg/day. Note that these dosages are for adults who are otherwise healthy and are on no interacting medicines. The dosage of diphenhydramine may need reducing in those with certain medical conditions or taking certain medicines.Therefore, medications like Benadryl (which is an OTC antihistamine) might be fine for the general population, but not for you. Benadryl and other OTC antihistamines can alter your mood and make it tempting to abuse it. If you require an antihistamine, you should use Allegra, Claritin or another type of non-sedating antihistamine.NyQuil takes about 30 minutes to start working. It can be taken at any time of day, but be aware that it can cause drowsiness. So you may need to aveoid using it during the day if it makes you too sleepy. NyQuil can be taken with or without food, but it may interact with other medications you take.The older, first-generation antihistamines, such as diphenhydramine (Benadryl, Nytol, Sominex), brompheniramine (Dimetapp), chlorpheniramine (Chlor-Trimeton) and doxylamine (Vicks NyQuil, Alka-Seltzer Plus) are effective in relieving allergic symptoms. However, they cause drowsiness and weaken the ability of the bladder to expel urine.

3. Safe: Nyquil and Benadryl are generally safe when used as directed. However, it is important to read the label carefully and follow the dosage instructions. 4. Widely available: Nyquil and Benadryl are available over-the-counter in most drug stores and pharmacies. They are affordable and can be purchased without a prescription.When combining Suboxone and Benadryl, you can develop severe sedation.[4] The two drugs work together on the central nervous system, slowing your breathing to such a degree that it stops altogether. You could be at risk for being overly sedated which can lead to falls, accidents, or even respiratory depression or overdose.NyQuil takes about 30 minutes to start working. It can be taken at any time of day, but be aware that it can cause drowsiness. So you may need to aveoid using it during the day if it makes you too sleepy. NyQuil can be taken with or without food, but it may interact with other medications you take.NyQuil can be taken with or without food. However, if you find that it upsets your stomach or causes nausea when you take a dose, food may help to make it better tolerated. ... It is a 'first-generation' antihistamine, similar to Benadryl. In addition to the alcohol that NyQuil contains, doxylamine is what causes you to feel tired after taking ...Dr. Robert Kwok answered. Claritin (loratadine) is a once-a-day medication, and does wear off some by night time. If nyquil, with its own antihistamine, is taken at night time, there should not be a big problem. Nyquil is usually used for just a few days during cold or flu symptoms. A doctor can evaluate prolonged or bothersome symptoms, to see ...

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Answer. The use of Abilify (aripiprazole) and Benadryl (diphenhydramine) may require monitoring as there is a moderate drug interaction between these two medications. There are actually two potential interactions between Abilify and Benadryl: Both can cause CNS (central nervous system) depression and can cause additive …However, Benadryl can also cause dry mouth, constipation, and urinary retention. Nyquil can cause drowsiness, dizziness, and nausea. Benadryl and Nyquil are both safe to take during pregnancy. Benadryl and Nyquil are both safe to take for children, but it is important to follow the dosage instructions carefully.Requirements for Safe Houses - Safe houses come in different types: defensive and offensive. But what are the requirements that define an effective safe house? Advertisement A safe...Antihistamines are considered safe to use. They are used for a wide range of symptoms including post nasal drip, congestion, and allergy symptoms. Claritin, Zyrtec, and Allegra all last 24 hours and are good options to combine with Wellbutrin if needed. While most antihistamines are considered safe with Wellbutrin, one exception may be …NyQuil by Vicks is a line of cold and flu medications formulated to be used at night. NyQuil contains a blend of ingredients to help relieve symptoms that can make it difficult to sleep. Several ingredients in NyQuil can also induce sleepiness. There are several important points to consider before using NyQuil to help get to sleep.Doses up to 100 mg have been safely used for the treatment of allergic reactions. However, as ZzzQuil is purely indicated for use as a sleep aid, dosages should not exceed 50 mg (30 ml). Doses above this have the risk of causing a "hangover" effect the next morning and more rarely, paradoxical reactions such as insomnia and restlessness.

If you're wondering whether it's safe to take Benadryl and Nyquil together, let me provide some insights. Both medications are commonly used for different purposes; Benadryl is an antihistamine that helps with allergies, while Nyquil is a cold and flu relief medication. While they can be effective on their own, combining them may not always ...Answer. There is no known drug interaction between azithromycin (Z-Pak) and Nyquil (acetaminophen, dextromethorphan, and doxylamine). They can be safely taken together. 'NyQuil Severe', which contains one additional ingredient when compared to the 'original' NyQuil, is also safe to take with a Z-Pak. Below, I discuss each medication in more detail.Risk of side effects. When it comes to taking Benadryl for sleep or allergies, there's also potential for some not-so-great side effects, says Dr. Katznelson; these can include mouth dryness, constipation, retaining urine, cognitive dysfunction (i.e. trouble thinking), and risk of seizure if you take too high of a dose.Botox and Dysport are safe to use in combination with benadryl. It is always wise to review any medications you are taking with your injector prior to treatment, particularly as there are some that can increase your risk for bruising.Time To Wait Between NyQuil Doses. NyQuil contains the following ingredients: Each ingredient in NyQuil has a duration of action of around 4 to 6 hours, although the sedative effects (which come from the sedating antihistamine doxylamine) have been known to last up to 8 hours in certain individuals. It is important to not take an additional ... diphenhydrAMINE tiZANidine. Applies to: Benadryl (diphenhydramine) and tizanidine. Using tiZANidine together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Taking Nyquil and Benadryl together can potentially increase the diphenhydramine level in your system beyond what is considered safe. Excessive amounts of diphenhydramine can lead to side effects such as drowsiness, dizziness, blurred vision, dry mouth, and …Best Answer. Can I give Childrens Benadryl with Childrens Nyquil? Wiki User. ∙ 13y ago.

little or no urinating. Common side effects of doxylamine may include: blurred vision; dry mouth, nose, or throat; constipation; or. mild dizziness or drowsiness. Side effects such as dry mouth, constipation, and confusion may be more likely in older adults. This is not a complete list of side effects and others may occur.

Benadryl is a name-brand medication whose primary active ingredient is diphenhydramine, an antihistamine. Although it is not specifically labeled for use in pets, it is commonly recommended and used by veterinarians "off label." Here's what you need to know about giving cats Benadryl. Can You Give a Cat Benadryl?Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect. 5. Tips. Benadryl may be taken with or without food. Take exactly as directed.Benadryl (diphenhydramine) Vicks NyQuil Severe Cold & Flu (acetaminophen/dextromethorphan/doxylamine/phenylephrine) Note: In certain …Cold medications can help with sleeplessness because the drugs usually contain doxylamine or diphenhydramine, two sedating antihistamines that can quickly cause drowsiness to set in. According to Susheel Patil, clinical director at Johns Hopkins Sleep Medicine, in the absence of a cold, "it may be all right for a few days to use OTC cold ...Thank. Dr. Hushang Haghighat answered. Specializes in Pediatric Hematology and Oncology. Yes: Both are for cold ,cough and congestion but nyquil is for night that make sedation to sleep so take theraflu in the morning and nyquil at night. Answered 1/8/2021.Aug 14, 2007 ... Whatever the merits of that confrontation, doctors say there is one lesson to take away: drugs like Benadryl should never be given to sedate a ...It is generally considered safe during pregnancy and has even been studied on its ability to help decrease symptoms of nausea experienced during pregnancy. The following formulas of NyQuil™ contain this ingredient: SEVERE VapoCOOL Nighttime Cough, Cold, and Flu Relief. Cold and Flu Nighttime Relief Liquicaps™. Cold and Flu Nighttime Relief ...

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Took 150 mg benadryl. 20 mg melatonin and nyquil. i cant keep my eyes open but also cant sleep. its been 6 hrs. can i take more benadryl? i need sleep. what could happen if you take both melatonin & nyquil together?: Melatonin & Nyquil: M of unknown age or medical history.How Benadryl makes sleeping easier. Antihistamines stop allergic reactions by blocking excess production of histamine in the immune system. Some also block histamine release in the brain. The ...No, you should not take Benadryl and Xanax together. Taking Xanax and Benadryl together can intensify side effects like dizziness, fatigue, drowsiness, inability to. concentrate, and lack of coordination. Combining the two can be especially dangerous for the elderly. Like many drug reactions, the effects of either medication can be intensified ...ALPRAZolam diphenhydrAMINE. Applies to: Xanax (alprazolam) and Benadryl (diphenhydramine) Using ALPRAZolam together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.U should be fine taking either. Nyquil usually had some sort of anti-histamine in it already so make sure u figure out how much u already took before adding more on top of it. The melatonin u could just take the normal dose. Or I would probably just drink more nyquil. Beautiful_fantasy2.Dec 27, 2022 · Benadryl (diphenhydramine) is also a first-generation antihistamine that can cause sedation or drowsiness. It is considered to be in the same class of drugs as the doxylamine that is found in NyQuil. Benadryl can also be used as a short-term sleeping aid, but it is also commonly used to treat allergies, allergic reactions, and itching. diphenhydrAMINE tiZANidine. Applies to: Benadryl (diphenhydramine) and tizanidine. Using tiZANidine together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Answer. There is not a drug interaction between Benadryl (diphenhydramine) and Paxil (paroxetine). However, using both medications together can increase the risk of sedation and drowsiness. Therefore, due to the risk of additive sedation, the combination should be used with caution. In most cases, Benadryl administration should only be done in ...Both Benadryl and Nyquil contain sedating antihistamines, such as diphenhydramine and doxylamine succinate, respectively. Combining these substances can increase the risk of excessive sedation and other side effects. Therefore, it is generally not recommended to take Benadryl and Nyquil together unless advised by a healthcare …It is a key ingredient of virtually all over-the-counter cough and cold formulations, including those sold as Robitussin, Benylyn, DayQuil/NyQuil, Delsym, Triaminic, and Theraflu.Benadryl (Diphenhydramine) received an overall rating of 7 out of 10 stars from 221 reviews. See what others have said about Benadryl (Diphenhydramine), including the effectiveness...Benadryl is an over-the-counter (OTC) syrup commonly used by people to alleviate the symptoms of cough or as an antihistamine to improve the symptoms of skin irritation. However, maintain caution as Benadryl while breastfeeding may be unsafe as it has mild sedative properties and may pass into the baby through the breastmilk. ….

Alternatives. Benadryl (diphenhydramine) and Unisom (doxylamine succinate) are sleep aids that can be purchased over the counter. Both medications are antihistamines that have sedative side effects. Generic versions are also available. These medications are meant to treat short-term sleep problems.Are your files safe in the cloud? Learn about cloud storage and if your files will be safe in the cloud. Advertisement The days of keeping all your documents, photos and music on y...Yes: That should present no problems. Yes: Aleve contains naproxen, whereas nyquil has an antihistamine which does not interefere. Some forms of nyquil contain Acetaminophen (as in tylenol) in which case you might not require aleve, or less need less. Yes: That should present no problems.They can raise your blood pressure. • Pseudoephedrine is not safe for kidney patients. Medications for cough and chest congestion . Okay to use: • Guaifenesin (Mucinex and Robitussin DM ) for cough and chest congestion. • The cough suppressant dextromethorphan (Delsym DM , Vicks Nyquil Cough Liquid ).50 mg. 100 mg. The typical hydroxyzine dosage for adults with insomnia is 50 mg daily, taken at least 30 minutes before bedtime. Your healthcare provider will recommend the appropriate dosage based on your condition. Meanwhile, Benadryl has two doses—25 mg and 50 mg. The average dose of Benadryl for sleep issues is 50 mg daily, taken orally.No, you should not take Benadryl and Xanax together. Taking Xanax and Benadryl together can intensify side effects like dizziness, fatigue, drowsiness, inability to. concentrate, and lack of coordination. Combining the two can be especially dangerous for the elderly. Like many drug reactions, the effects of either medication can be intensified ...Montelukast (Singular) is an oral medication used to treat asthma and seasonal allergies. Medications that can interact with montelukast include gemfibrozil (Lopid), certain seizure medications, and rifampin. It’s OK to take montelukast with certain antihistamines, such as cetirizine (Zyrtec). But some people may experience excessive ...Jan 15, 2022 ... Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that ...50 mg. 100 mg. The typical hydroxyzine dosage for adults with insomnia is 50 mg daily, taken at least 30 minutes before bedtime. Your healthcare provider will recommend the appropriate dosage based on your condition. Meanwhile, Benadryl has two doses—25 mg and 50 mg. The average dose of Benadryl for sleep issues is 50 mg daily, taken orally. Is it safe to take nyquil with benadryl, Key takeaways: Gabapentin (Neurontin) can interact with medications and substances that make you sleepy. These include opioids, benzodiazepines, and alcohol. Gabapentin can interact with some over-the-counter (OTC) medications and supplements. These include antihistamines as well as products that contain magnesium or aluminum., Bupropion can interact with alcohol and lower your alcohol tolerance. It can also cause false positive results for amphetamine and methamphetamine on a urine drug test. Talk to your healthcare provider to learn about bupropion interactions. If you take a medication that interacts with bupropion, you may only need more monitoring., Doxylamine (Unisom SleepTabs) is generally safe to take. But it might not be the best choice for older adults ages 65 years of age or older because they're at higher risk for side effects, like dizziness, confusion, and next-day sleepiness.In addition, doxylamine (Unisom SleepTabs) might not be right for people who've certain medical conditions, such as breathing problems (e.g., emphysema or ..., As mentioned above, it is safe to take Benadryl with Theraflu, as long as the specific Theraflu product you are using doesn't also contain an antihistamine. Summary. If you plan to take Benadryl and a Theraflu product together, be aware that nighttime formulations of TheraFlu products all contain diphenhydramine already, and if you're using ..., Diphenhydramine (Benadryl) Safe throughout pregnancy. Watch out for extra ingredients. Many cold and flu medications treat more symptoms than you may be experiencing. For example, Tylenol Cold Multi-Symptom treats headaches, fever, body aches, cough, chest congestion, stuffy nose, and more. If you just have a stuffy nose, this is more ..., diphenhydrAMINE tiZANidine. Applies to: Benadryl (diphenhydramine) and tizanidine. Using tiZANidine together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., Tylenol can be taken on its own, but there are many multi-symptom cold & flu remedies that also contain acetaminophen as an active ingredient. These include: Alka-Seltzer Plus Cold & Flu. Contac Cold + Flu. Coricidin HBP Cold & Flu. Equate Cold & Flu Multi-Symptom Relief. Mucines Cold & Flu. Robitussin Multi-Symptom Cough Cold + Flu., Can you take OTC cold and flu medicines like NyQuil with Paxlovid? Yes. In general, it's OK to take over-the-counter (OTC) cold and flu medicines with Paxlovid. OTC cold and flu medicines usually contain one or more of these ingredients: Dextromethorphan, a cough suppressant. Guaifenesin, an expectorant. An antihistamine like doxylamine or ..., The concern with using NyQuil and Zyrtec at the same time is the potential for additive side effects from each, which could include: Drowsiness. Dry mouth. Dry eyes. Sedation. This interaction, for most people, wouldn't be considered too serious, but it is a drug interaction nonetheless, so is important to be aware of., A report published in JAMA Internal Medicine several years ago highlighted a link between long-term use of anticholinergic medications like Benadryl and dementia. While this study and other observational studies have also found this association, it doesn't prove that these drugs cause dementia. But we do know that anticholinergic drugs can cause confusion and increase fall risk in older people., Benadryl. A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis. Allergies., Ask your doctor or pharmacist how much acetaminophen is safe to take. ... Does Vicks Nyquil Nighttime Relief 6.25 Mg-15 Mg-325 Mg/15 Ml Oral Liquid interact with other drugs you are taking?, Nyquil for kids is an over-the-counter cold and cough medication that children under 12 age should not consume unless directed otherwise by the doctor. Drowsiness, stomach pain, nausea, and vomiting are some of the side effects of this medication that parents should note. Also, some children can develop an allergic reaction to Nyquil., Diphenhydramine (Benadryl) Safe throughout pregnancy. Watch out for extra ingredients. Many cold and flu medications treat more symptoms than you may be experiencing. For example, Tylenol Cold Multi-Symptom treats headaches, fever, body aches, cough, chest congestion, stuffy nose, and more. If you just have a stuffy nose, this is more ..., Answers. WI. WildcatVet 8 April 2021. NyQuil is not addictive but you can become dependent on it and stopping it could cause discontinuation symptoms such as anxiety, insomnia, restlessness, and shaking/tremors. Before using it long term I'd advise getting an okay from your doctor or pharmacist., Paxil is an SSRI (selective serotonin reuptake inhibitor) that does have a few drug interactions and considerations with over-the-counter medication that are important to be aware of. There are many that are safe to take. They include: Antihistamines (e.g. Claritin, Allegra, Benadryl, Zyrtec etc...) Tylenol (acetaminophen) Mucinex (guaifenesin ..., But before you overdo it on sleep supplements, it's important to know which medications are safe to take together---and which aren't. Melatonin and Benadryl are both common, over-the-counter meds used by many to support deeper sleep. On their own, each is a relatively mild option for short-term sleep support., Donation. 15 Days Left. Prednisone is widely used to reduce inflammation in various conditions. It works by suppressing the immune response and reducing the production of inflammatory substances in the body. Prednisone can effectively manage inflammation associated with autoimmune diseases, allergies, and certain respiratory conditions., A doctor has provided 1 answer. is it safe to take clariton 24 hour allergy medicine and dayquil/nyquil? would i get too sleep?: No: I would not advise taking theses medications together. They all ha., Benadryl. A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis. Allergies., Taking Benadryl (diphenhydramine) every day is generally not recommended. If you are using Benadryl to help you sleep, talk to your doctor about your sleeping issues to determine the cause and/or find an alternative sleep-aid. If you are using Benadryl for allergies, it may be more beneficial to should take a newer and safer alternative, such ..., Yes, Mucinex and Nyquil can be taken together because they contain different ingredients, but Mucinex DM and Nyquil should not be taken together because they share a common ingredient, dextromethorphan. Instead of taking Mucinex DM and Nyquil together you should just take Nyquil. Mucinex contains guaifenesin which is an expectorant and its main purpose is to thin out the mucus in your airways ..., They are generally considered safe to take together. It is important to note that ritonavir (again, a component of Paxlovid), is a minor inhibitor of another enzyme, CYP2D6, which is responsible for metabolizing the cough suppressant in NyQuil & DayQuil, dextromethorphan. However, most studies note that the inhibition of CYP2D6 is weak, and any ..., OK Benedryl+Vyvanse: Benedryl is an 'sedating' antihistamine and is safe with Vyvanse (lisdexamfetamine) (add med) benedryl is best dosed @ night. Safe but not advised: Benadryl (diphenhydramine) is too sedating, resulting often in some cognitive suppression. The reason for taking the Vyvanse in the 1st place is to enhance cognition., It can be taken orally but also comes in a topical form. In addition to treating allergy symptoms, Benadryl can help with insomnia due to the sedation it causes. Benadryl begins to work about 20 to 30 minutes after taking by mouth and maximum blood concentrations are reached after 1 to 2 hours., Diphenhydramine, the same antihistamine found in Benadryl, will likely put you to sleep, though you may pay the price once you land. "It makes us feel really groggy when we wake up, and it can ..., Product causes insomnia and restlessness in some users (backed by 5 comments) Product causes nausea, dizziness and headaches in some users (backed by 4 comments) Product causes anxiety and nightmares in some users (backed by 3 comments) If you'd like to summon me to ask about a product, just make a post with its link and tag me, like in this ..., Tylenol. Benadryl Cold/Flu. Alka-Seltzer Plus Cold & Flu. Theraflu Severe Cold & Cough. NyQuil. Coricidin HBP Cold & Flu. Vicks DayQuil Cold & Flu. Tylenol (or generic acetaminophen) can be combined with ibuprofen. You can also take Tylenol while taking naproxen., diphenhydrAMINE morphine. Applies to: Benadryl (diphenhydramine) and morphine. Using diphenhydrAMINE together with morphine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., Stop use and ask a healthcare provider if: Pain or cough worsens or lasts more than seven days. Fever worsens or lasts more than three days. Redness or swelling is present in area causing pain. New …, dextromethorphan food. Applies to: Vicks NyQuil HBP Cold & Flu (acetaminophen / dextromethorphan / doxylamine) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment., NyQuil: in some people it has a stimulating effect and won't matter if you take melatonin. Look OTC at cold drugs that can be taken at night. What We Treat ... Took 150 mg benadryl. 20 mg melatonin and nyquil. i cant keep my eyes open but also cant sleep. Its been 6 hrs. Can i take more benadryl? I Need sleep. A doctor has provided 1 answer. A ..., Antihistamines are considered safe to use. They are used for a wide range of symptoms including post nasal drip, congestion, and allergy symptoms. Claritin, Zyrtec, and Allegra all last 24 hours and are good options to combine with Wellbutrin if needed. While most antihistamines are considered safe with Wellbutrin, one exception may be Benadryl.